Probing the Limits of Selectivity in a Recognition-Mediated Reaction Network Embedded within a Dynamic Covalent Library.

نویسندگان

  • Tamara Kosikova
  • Harry Mackenzie
  • Douglas Philp
چکیده

Two recognition-mediated reaction processes operating through reactive binary complexes drive resolution of a 24-component dynamic covalent library, assembled from individual aldehydes and nucleophiles. The effectiveness of the library resolution and selective amplification of one recognition-enabled species over another is limited by the difference in the rates of the recognition-mediated reactive processes and the strength of the recognition processes employed in the dynamic system.

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عنوان ژورنال:
  • Chemistry

دوره 22 5  شماره 

صفحات  -

تاریخ انتشار 2016